Oxford University: Vaccines Cause Autoinflammatory Disorders
Oxford University: Vaccines Cause Autoinflammatory Disorders by Baxter Dmitry – Your News Wire
Doctors should not take a one-size-fits-all approach to vaccination schedules, and should be very cautious when administering vaccines to patients with different health concerns and medical histories, according to a new academic study published by the Oxford University journal Rheumatology.
The study investigated the reactions to vaccines in patients with cryopyrin-associated periodic syndromes (CAPS) and found that many have “moderate to severe reactions that warrant caution and additional research.“
The study lends weight to calls from vaccine skeptics for further studies into vaccine safety involving cost/benefit analyses on each and every vaccination. Big Pharma must not be allowed to operate outside the usual legal parameters applied to every other industry and they certainly must not be allowed to regulate themselves.
Contemporary Pediatrics reports: Although the Advisory Committee on Immunization Practices (ACIP) recommends that patients with CAPS—particularly familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and neonatal onset multisystem inflammatory disease (NOMID)—receive vaccinations against pneumococcal disease, tetanus, and influenza when treated with immunosuppressive medications, the study investigated the safety of these vaccines in the particular patient population.
Patients with CAPS may have an increased susceptibility to pneumococcal pneumonia, similar to other patients with immune-related disorders, according to the report.
Previous research revealed unusually severe local and systemic reactions in CAPS patients related to vaccination that led to this study. Researchers first analyzed case studies of 7 CAPS patients vaccinated with the pneumococcal series. Six of those patients were also being following in the B-CONFIDENT (Clinical Outcomes and Safety: A Registry Study of Ilaris [Canakinumab] Patients) registry, a long-term prospective observational study of patients treated with canakinumab.
This involvement led the study authors to expand their study to investigate the safety of pneumococcal and other vaccines within the entire B-CONFIDENT registry.
The registry followed 285 patients, 68 of whom fit the CAPS criteria desired by the study authors. Those 68 CAPS patients received a total of 159 vaccine injections across 9 countries—81% influenza, 26% pneumococcal, 18% tetanus and diphtheria, and 16% against other unspecified pathogens.
Over the study period, the researchers noted that 43 CAPS patients received more than 1 vaccination, and that 22 injections in 18 CAPS patients resulted in at least 1 vaccine reaction.